Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks

Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks

Abstract Background Breast (mammary) cancers in human (BC) and canine (CMT) patients share clinical, pathological, and molecular similarities that suggest dogs may be a useful translational model. Many cancers, including BC, shed exosomes that contain microRNAs (miRs) into the microenvironment and c...

Full description

Bibliographic Details
Main Authors: Eric J. Fish, Kristopher J. Irizarry, Patricia DeInnocentes, Connor J. Ellis, Nripesh Prasad, Anthony G. Moss, R. Curt Bird
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
Canine
Mammary cancer
microRNA
miR-18a
Estrogen receptor
Exosome
Online Access:http://link.springer.com/article/10.1186/s12885-018-4750-6

Internet

http://link.springer.com/article/10.1186/s12885-018-4750-6

Similar Items