Production of mannosylglycerate in Saccharomyces cerevisiae by metabolic engineering and bioprocess optimization

Production of mannosylglycerate in Saccharomyces cerevisiae by metabolic engineering and bioprocess optimization

Abstract Background Mannosylglycerate (MG) is one of the most widespread compatible solutes among marine microorganisms adapted to hot environments. This ionic solute holds excellent ability to protect proteins against thermal denaturation, hence a large number of biotechnological and clinical appli...

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Bibliographic Details
Main Authors: Cristiana Faria, Nuno Borges, Isabel Rocha, Helena Santos
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Microbial Cell Factories
Subjects:
Mannosylglycerate
Compatible solute
GDP-mannose
Yeast cell factory
Metabolic engineering
Chemostat cultivation
Online Access:http://link.springer.com/article/10.1186/s12934-018-1023-7

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http://link.springer.com/article/10.1186/s12934-018-1023-7

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