Regulation of Antigenic Variation by <i>Trypanosoma brucei</i> Telomere Proteins Depends on Their Unique DNA Binding Activities

Regulation of Antigenic Variation by <i>Trypanosoma brucei</i> Telomere Proteins Depends on Their Unique DNA Binding Activities

<i>Trypanosoma brucei</i> causes human African trypanosomiasis and regularly switches its major surface antigen, Variant Surface Glycoprotein (VSG), to evade the host immune response. Such antigenic variation is a key pathogenesis mechanism that enables <i>T. brucei</i> to es...

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Bibliographic Details
Main Authors: Bibo Li, Yanxiang Zhao
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
antigenic variation
<i>Trypanosoma brucei</i>
VSG
telomere
TRF
RAP1
Online Access:https://www.mdpi.com/2076-0817/10/8/967

Internet

https://www.mdpi.com/2076-0817/10/8/967

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