The mechanism of phospholipase Cγ1 activation

The mechanism of phospholipase Cγ1 activation

Phospholipase C is an enzyme which catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) into second messengers inositol-1,4,5-triphosphate (Ins(1,4,5)P3) and diacylglycerol (DAG). These messengers then promote the activation of protein kinase C and release of Ca2 from intra...

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Bibliographic Details
Main Authors: Paweł Krawczyk, Janusz Matuszyk
Format: Article
Language:English
Published: Index Copernicus International S.A. 2011-08-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
fosfolipaza Cγ1
mechanizm aktywacji fosfolipazy Cγ1
metabolizm fosfatydyloinozytolu
receptorowe kinazy tyrozynowe
phospholipase Cγ1
activation mechanism of phospholipase Cγ1
phosphoinositide metabolism
receptor tyrosine kinase
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=954782

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