Extensive Metabolic Remodeling Differentiates Non-pathogenic and Pathogenic Growth Forms of the Dimorphic Pathogen Talaromyces marneffei

Extensive Metabolic Remodeling Differentiates Non-pathogenic and Pathogenic Growth Forms of the Dimorphic Pathogen Talaromyces marneffei

Fungal infections are an increasing public health problem, particularly in immunocompromised individuals. While these pathogenic fungi show polyphyletic origins with closely related non-pathogenic species, many undergo morphological transitions to produce pathogenic cell types that are associated wi...

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Bibliographic Details
Main Authors: Shivani Pasricha, James I. MacRae, Hwa H. Chua, Jenny Chambers, Kylie J. Boyce, Malcolm J. McConville, Alex Andrianopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Talaromyces marneffei
central carbon metabolism
metabolomics
nutrient acquisition
pathogenic fungi
dimorphic switching
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00368/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00368/full

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