Cognition, learning behaviour and hippocampal synaptic plasticity are not disrupted in mice over-expressing the cholesterol transporter ABCG1

<p>Abstract</p> <p>Background</p> <p>Cognitive deficits are a hallmark feature of both Down Syndrome (DS) and Alzheimer's Disease (AD). Extra copies of the genes on chromosome 21 may also play an important role in the accelerated onset of AD in DS individuals. Grow...

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Bibliographic Details
Main Authors: Eadie Brennan D, Kannangara Timal S, Parkinson Pamela F, Burgess Braydon L, Wellington Cheryl L, Christie Brian R
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Lipids in Health and Disease
Online Access:http://www.lipidworld.com/content/8/1/5