Sonothrombolysis with BR38 Microbubbles Improves Microvascular Patency in a Rat Model of Stroke.

Early recanalization of large cerebral vessels in ischemic stroke is associated with improved clinical outcome, however persisting hypoperfusion leads to poor clinical recovery despite large vessel recanalization. Limited experimental sonothrombolysis studies have shown that addition of microbubbles...

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Bibliographic Details
Main Authors: Nadine Schleicher, Amelia J Tomkins, Marian Kampschulte, Jean-Marc Hyvelin, Catherine Botteron, Martin Juenemann, Mesut Yeniguen, Gabriele A Krombach, Manfred Kaps, Neil J Spratt, Tibo Gerriets, Max Nedelmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4831751?pdf=render