Endoplasmic reticulum, oxidative stress and their complex crosstalk in neurodegeneration: proteostasis, signaling pathways and molecular chaperones

Endoplasmic reticulum, oxidative stress and their complex crosstalk in neurodegeneration: proteostasis, signaling pathways and molecular chaperones

Cellular stress caused by protein misfolding, aggregation and redox imbalance is typical of neurodegenerative disorders such as Parkinson’s disease (PD) and Amyotrophic Lateral Sclerosis (ALS). Activation of quality control systems, including endoplasmic reticulum (ER)-mediated degradation, and reac...

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Bibliographic Details
Main Authors: Giulia Ambrosi, Pamela Milani
Format: Article
Language:English
Published: AIMS Press 2017-10-01
Series:AIMS Molecular Science
Subjects:
Parkinson’s Disease
Amyotrophic Lateral Sclerosis
endoplasmic reticulum
oxidative stress
MAPK
NFkB
autophagy
molecular chaperones
Online Access:http://www.aimspress.com/Molecular/article/1660/fulltext.html

Internet

http://www.aimspress.com/Molecular/article/1660/fulltext.html

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