Integrin β3/Akt signaling contributes to platelet-induced hemangioendothelioma growth

Abstract Hemangioendothelioma (HE) is a type of angiomatous lesions that features endothelial cell proliferation. Understanding the mechanisms orchestrating HE angiogenesis can provide therapeutic insights. It has been shown that platelets can support normal and malignant endothelial cells during an...

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Bibliographic Details
Main Authors: Rui Gu, Xin Sun, Yijie Chi, Qishuang Zhou, Hongkai Xiang, Dale B. Bosco, Xinhe Lai, Caixia Qin, Kwok-Fai So, Yi Ren, Xiao-Ming Chen
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06927-0