Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model

Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model

Malignant cells cultured in three-dimensional (3D) models have been found to be phenotypically and biochemically different from their counterparts cultured conventionally. Since most of these studies employed solid tumor types, how 3D culture affects multiple myeloma (MM) cells is not well understoo...

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Bibliographic Details
Main Authors: Yung-Hsing Huang, Ommoleila Molavi, Abdulraheem Alshareef, Moinul Haque, Qian Wang, Michael P. Chu, Christopher P. Venner, Irwindeep Sandhu, Anthea C. Peters, Afsaneh Lavasanifar, Raymond Lai
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
3D culture
multiple myeloma
STAT
bortezomib
CETSA
Stattic
Online Access:http://www.mdpi.com/2072-6694/10/6/206

Internet

http://www.mdpi.com/2072-6694/10/6/206

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