PD-L1 Expression Affects Neoantigen Presentation

Summary: Although PD-L1 expression on tumor is related to the prognosis of immune checkpoint blockade (ICB) therapy, a recent study also demonstrated clinical benefits even in patients without PD-L1 expression. To understand the relationship between innate resistance and antitumor cytotoxic T lympho...

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Bibliographic Details
Main Authors: Masahiro Okada, Kanako Shimizu, Tomonori Iyoda, Shogo Ueda, Jun Shinga, Yoshiki Mochizuki, Takashi Watanabe, Osamu Ohara, Shin-ichiro Fujii
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304235