Genome-wide RNAi screen in Drosophila reveals Enok as a novel trithorax group regulator

Genome-wide RNAi screen in Drosophila reveals Enok as a novel trithorax group regulator

Abstract Background Polycomb group (PcG) and trithorax group (trxG) proteins contribute to the specialization of cell types by maintaining differential gene expression patterns. Initially discovered as positive regulators of HOX genes in forward genetic screens, trxG counteracts PcG-mediated repress...

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Bibliographic Details
Main Authors: Zain Umer, Jawad Akhtar, Muhammad Haider Farooq Khan, Najma Shaheen, Muhammad Abdul Haseeb, Khalida Mazhar, Aziz Mithani, Saima Anwar, Muhammad Tariq
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Epigenetics & Chromatin
Subjects:
Epigenetic cellular memory
Gene regulation
trithorax group
Polycomb group
Enok
Genome-wide RNAi screen
Online Access:http://link.springer.com/article/10.1186/s13072-019-0301-x

Internet

http://link.springer.com/article/10.1186/s13072-019-0301-x

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