Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.
Bronchial asthma is a chronic airway inflammatory condition with high morbidity, and effective treatments for asthma are limited. Allergen-specific immunotherapy can only induce peripheral immune tolerance and is not sustainable. Exploring new therapeutic strategies is of great clinical importance....
Main Authors: | Yan Chen, Jin Zhang, Yong Lu, Libo Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4393286?pdf=render |
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