Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.

Bronchial asthma is a chronic airway inflammatory condition with high morbidity, and effective treatments for asthma are limited. Allergen-specific immunotherapy can only induce peripheral immune tolerance and is not sustainable. Exploring new therapeutic strategies is of great clinical importance....

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Bibliographic Details
Main Authors: Yan Chen, Jin Zhang, Yong Lu, Libo Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4393286?pdf=render