Postnatal Overnutrition Induces Changes in Synaptic Transmission to Leptin Receptor-Expressing Neurons in the Arcuate Nucleus of Female Mice

Postnatal Overnutrition Induces Changes in Synaptic Transmission to Leptin Receptor-Expressing Neurons in the Arcuate Nucleus of Female Mice

The adipocyte-derived hormone leptin is a potent neurotrophic factor that contributes to the neural plasticity and development of feeding circuitry, particularly in the arcuate nucleus of the hypothalamus (ARH). Postnatal overnutrition affects leptin secretion and sensitivity, but whether postnatal...

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Bibliographic Details
Main Authors: Thais Tessari Zampieri, Tabata Mariz Bohlen, Marina Augusto Silveira, Larissa Campista Lana, Daniella G. de Paula, Jose Donato, Renata Frazao
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Nutrients
Subjects:
hypothalamus
development
overweight
puberty
Online Access:https://www.mdpi.com/2072-6643/12/8/2425

Internet

https://www.mdpi.com/2072-6643/12/8/2425

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