MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult
<p>Abstract</p> <p>Background</p> <p>An endotoxin insult mimics a severe peripheral infection and recent evidence suggests that a single exposure can cause long-term cognitive deficits. A peripheral injection of LPS results in production of pro-inflammatory cytokines, s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-08-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/5/1/35 |