Asymmetrically Positioned Flagellar Control Units Regulate Human Sperm Rotation

Summary: Ion channels control sperm navigation within the female reproductive tract and, thus, are critical for their ability to find and fertilize an egg. The flagellar calcium channel CatSper controls sperm hyperactivated motility and is dependent on an alkaline cytoplasmic pH. The latter is accom...

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Bibliographic Details
Main Authors: Melissa R. Miller, Samuel J. Kenny, Nadja Mannowetz, Steven A. Mansell, Michal Wojcik, Sarah Mendoza, Robert S. Zucker, Ke Xu, Polina V. Lishko
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718312701