PiiL: visualization of DNA methylation and gene expression data in gene pathways

Abstract Background DNA methylation is a major mechanism involved in the epigenetic state of a cell. It has been observed that the methylation status of certain CpG sites close to or within a gene can directly affect its expression, either by silencing or, in some cases, up-regulating transcription....

Full description

Bibliographic Details
Main Authors: Behrooz Torabi Moghadam, Neda Zamani, Jan Komorowski, Manfred Grabherr
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-3950-9