Pre- and post-sequencing recommendations for functional annotation of human fecal metagenomes

Pre- and post-sequencing recommendations for functional annotation of human fecal metagenomes

Abstract Background Shotgun metagenomes are often assembled prior to annotation of genes which biases the functional capacity of a community towards its most abundant members. For an unbiased assessment of community function, short reads need to be mapped directly to a gene or protein database. The...

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Bibliographic Details
Main Authors: Michelle L. Treiber, Diana H. Taft, Ian Korf, David A. Mills, Danielle G. Lemay
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Metagenomes
Metagenomics
Fecal
Stool
Human
Functional annotation
Online Access:http://link.springer.com/article/10.1186/s12859-020-3416-y

Internet

http://link.springer.com/article/10.1186/s12859-020-3416-y

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