Repeated immune activation with low-dose lipopolysaccharide attenuates the severity of Huntington's disease in R6/2 transgenic mice

Huntington's disease (HD) is a neurodegenerative disorder caused by a mutation in the huntingtin gene. Previously, therapeutic approaches using anti-inflammatory agents were reportedly not effective for preventing HD progression. Since whether immune responses contribute to the onset of HD is n...

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Bibliographic Details
Main Authors: Sung Won Lee, Hyun Jung Park, Wooseok Im, Manho Kim, Seokmann Hong
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2018.1473291