In vivo mutational characterization of DndE involved in DNA phosphorothioate modification.

DNA phosphorothioate (PT) modification is a recently identified epigenetic modification that occurs in the sugar-phosphate backbone of prokaryotic DNA. Previous studies have demonstrated that DNA PT modification is governed by the five DndABCDE proteins in a sequence-selective and RP stereo-specific...

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Bibliographic Details
Main Authors: Chongde Lai, Xiaolin Wu, Chao Chen, Teng Huang, Xiaolin Xiong, Shuangju Wu, Meijia Gu, Zixin Deng, Xi Chen, Shi Chen, Lianrong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182426?pdf=render