Inherent promoter bidirectionality facilitates maintenance of sequence integrity and transcription of parasitic DNA in mammalian genomes
<p>Abstract</p> <p>Background</p> <p>Many mammalian genes are arranged in a bidirectional manner, sharing a common promoter and regulatory elements. This is especially true for promoters containing a CpG island, usually unmethylated and associated with an 'open...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/10/498 |