Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma

Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is the most common malignant epithelial tumor in the oral cavity. Emerging evidence has demonstrated the important function roles of long noncoding RNAs (lncRNAs) in human cancers. LncRNA promoter of CDKN1A antisense DNA damage activated RNA (PANDAR) functions as...

Full description

Bibliographic Details
Main Authors: Tingting Jia, Fengze Wang, Bo Qiao, Yipeng Ren, Lejun Xing, Haizhong Zhang, Hongbo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
CRISPR-dCas9
oral squamous cell carcinoma
PANDAR
SRFS7
PIM1
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.653787/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.653787/full

Similar Items