Stem Cell Factor in Combination with Granulocyte Colony-Stimulating Factor reduces Cerebral Capillary Thrombosis in a Mouse Model of CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a cerebral small vascular disease caused by NOTCH3 mutation-induced vascular smooth muscle cell (VSMC) degeneration, leading to ischemic stroke and vascular dementia. Our previous study has demons...

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Bibliographic Details
Main Authors: Suning Ping, Xuecheng Qiu, Maria E Gonzalez-Toledo, Xiaoyun Liu, Li-Ru Zhao
Format: Article
Language:English
Published: SAGE Publishing 2018-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718766460