KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study

Abstract Background KLK10 exon 3 hypermethylation correlated to tumor-specific lack of KLK10 expression in cancer cell lines and primary tumors. In the present study we investigate the possible role of KLK10 exon 3 methylation in ovarian tumor diagnosis and prognosis. Results Qualitative methylation...

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Bibliographic Details
Main Authors: Mustafa A. El Sherbini, Amal A. Mansour, Maha M. Sallam, Emtiaz A. Shaban, Zeinab A. Shehab ElDin, Amr H. El-Shalakany
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Ovarian Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13048-018-0407-y