Comparative modeling and docking studies of p16ink4/Cyclin D1/Rb pathway genes in lung cancer revealed functionally interactive residue of RB1 and its functional partner E2F1

Comparative modeling and docking studies of p16ink4/Cyclin D1/Rb pathway genes in lung cancer revealed functionally interactive residue of RB1 and its functional partner E2F1

<p>Abstract</p> <p>Background</p> <p>Lung cancer is the major cause of mortality worldwide. Major signalling pathways that could play significant role in lung cancer therapy include (1) Growth promoting pathways (Epidermal Growth Factor Receptor/Ras/ PhosphatidylInosito...

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Bibliographic Details
Main Authors: e Zahra Syeda Naqsh, Khattak Naureen Aslam, Mir Asif
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/10/1/1

Internet

http://www.tbiomed.com/content/10/1/1

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