Antioxidant Defense, Redox Homeostasis, and Oxidative Damage in Children With Ataxia Telangiectasia and Nijmegen Breakage Syndrome

Antioxidant Defense, Redox Homeostasis, and Oxidative Damage in Children With Ataxia Telangiectasia and Nijmegen Breakage Syndrome

Ataxia-telangiectasia (AT) and Nijmegen breakage syndrome (NBS) belong to a group of primary immunodeficiency diseases (PI) characterized by premature aging, cerebral degeneration, immunoglobulin deficiency and higher cancer susceptibility. Despite the fact that oxidative stress has been demonstrate...

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Bibliographic Details
Main Authors: Mateusz Maciejczyk, Edyta Heropolitanska-Pliszka, Barbara Pietrucha, Jolanta Sawicka-Powierza, Ewa Bernatowska, Beata Wolska-Kusnierz, Małgorzata Pac, Halina Car, Anna Zalewska, Bozena Mikoluc
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
ataxia-telangiectasia (AT)
nijmegen breakage syndrome (NBS)
oxidative stress
oxidative damage
antioxidants
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02322/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02322/full

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