Urinary Metabolic Profile of Patients with Transfusion-Dependent β-Thalassemia Major Undergoing Deferasirox Therapy

Urinary Metabolic Profile of Patients with Transfusion-Dependent β-Thalassemia Major Undergoing Deferasirox Therapy

Introduction: Renal dysfunction is a frequent complication in patients suffering from β-thalassemia major (β-TM). The aim of this study was to analyze the renal function and urine metabolomic profile of β-TM patients undergoing transfusions and deferasirox (DFX) therapy, in order to better character...

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Bibliographic Details
Main Authors: Giovanna Capolongo, Miriam Zacchia, Amerigo Beneduci, Silvia Costantini, Patrizia Cinque, Anna Spasiano, Giuseppina De Luca, Maria Enrica Di Pietro, Paolo Ricchi, Francesco Trepiccione, Giovambattista Capasso, Aldo Filosa
Format: Article
Language:English
Published: Karger Publishers 2020-05-01
Series:Kidney & Blood Pressure Research
Subjects:
β-thalassemia major
metabolomics
urinomics
tubular function
renal disease
Online Access:https://www.karger.com/Article/FullText/507369

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https://www.karger.com/Article/FullText/507369

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