Strategically targeting MYC in cancer [version 1; referees: 2 approved]

MYC is a major driver of cancer cell growth and mediates a transcriptional program spanning cell growth, the cell cycle, metabolism, and cell survival. Many efforts have been made to deliberately target MYC for cancer therapy. A variety of compounds have been generated to inhibit MYC function or sta...

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Bibliographic Details
Main Authors: Valeriya Posternak, Michael D. Cole
Format: Article
Language:English
Published: F1000 Research Ltd 2016-03-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-408/v1