Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens.

Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens.

Patient-derived xenograft (PDX) models generated from surgical specimens are gaining popularity as preclinical models of cancer. However, establishment of PDX lines from small cell lung cancer (SCLC) patients is difficult due to very limited amount of available biopsy material. We asked whether SCLC...

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Bibliographic Details
Main Authors: Tracy L Leong, Kieren D Marini, Fernando J Rossello, Samantha N Jayasekara, Prudence A Russell, Zdenka Prodanovic, Beena Kumar, Vinod Ganju, Muhammad Alamgeer, Louis B Irving, Daniel P Steinfort, Craig D Peacock, Jason E Cain, Anette Szczepny, D Neil Watkins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4156408?pdf=render

Internet

http://europepmc.org/articles/PMC4156408?pdf=render

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