Production of Cloned Miniature Pigs Expressing High Levels of Human Apolipoprotein(a) in Plasma.

High lipoprotein(a) [Lp(a)] levels are a major risk factor for the development of atherosclerosis. However, because apolipoprotein(a) [apo(a)], the unique component of Lp(a), is found only in primates and humans, the study of human Lp(a) has been hampered due to the lack of appropriate animal models...

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Bibliographic Details
Main Authors: Masayuki Ozawa, Takehiro Himaki, Shoji Ookutsu, Yamato Mizobe, Junki Ogawa, Kazuchika Miyoshi, Akira Yabuki, Jianglin Fan, Mitsutoshi Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4492603?pdf=render