Nucleotide-induced conformational dynamics in ABC transporters from structure-based coarse grained modelling.
ATP-binding cassette (ABC) transporters are integral membrane proteins which mediate the exchange of diverse substrates across membranes powered by ATP molecules. Our understanding of their activity is still hampered since the conformational dynamics underlying the operation of such proteins cannot...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-02-01
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| Series: | Frontiers in Physics |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphy.2016.00003/full |