The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps) in INO80, showing that Arp8 and Arp4 module sense the DNA length separating...
Main Authors: | Sandipan Brahma, Mzwanele Ngubo, Somnath Paul, Maheshi Udugama, Blaine Bartholomew |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-08-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05710-7 |
Similar Items
-
Structural biochemistry of the INO80 chromatin remodeler reveals an unexpected function of its two subunits Arp4 and Arp8
by: Fenn, Sebastian
Published: (2011) -
THE UNIQUE STRUCTURE AND MECHANISM OF INO80 - AN ATP DEPENDENT REMODELER OF THE HISTONE EXCHANGER FAMILY
by: Udugama, Maheshi Imalka
Published: (2010) -
MODES OF NUCLEOSOME INTERACTION AND MECHANISMS OF THE SACCHAROMYCES CEREVISIAE CHROMATIN REMODELERS INO80 AND ISW1A
by: Brahma, Sandipan
Published: (2016) -
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers
by: Sandipan Brahma, et al.
Published: (2017-06-01) -
Interaction of the Chromatin Remodeling Protein hINO80 with DNA.
by: Shweta Mendiratta, et al.
Published: (2016-01-01)