The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling

INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps)  in INO80, showing that Arp8 and Arp4 module sense the DNA length separating...

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Bibliographic Details
Main Authors: Sandipan Brahma, Mzwanele Ngubo, Somnath Paul, Maheshi Udugama, Blaine Bartholomew
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05710-7