Can clinical and urodynamic parameters predict the occurrence of neutralizing antibodies in therapy failure of intradetrusor onabotulinumtoxin A injections in patients with spinal cord injury?

Can clinical and urodynamic parameters predict the occurrence of neutralizing antibodies in therapy failure of intradetrusor onabotulinumtoxin A injections in patients with spinal cord injury?

Abstract Background The aim of the study was to clarify whether clinical and/or urodynamic parameters could be used to infer the probability of neutralizing antibody (NAb) formation as a possible cause of therapy failure (non-response, NR) in patients with neurogenic detrusor overactivity (NDO) due...

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Bibliographic Details
Main Authors: Christian Tiburtius, Ralf Böthig, Birgitt Kowald, Sven Hirschfeld, Roland Thietje
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Urology
Subjects:
Neurogenic bladder
Spinal cord injury, Botulinum neurotoxin a
Therapy failure
Overactive detrusor function
Online Access:http://link.springer.com/article/10.1186/s12894-020-00683-6

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http://link.springer.com/article/10.1186/s12894-020-00683-6

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