Amifostine reduces the seminiferous epithelium damage in doxorubicin-treated prepubertal rats without improving the fertility status

<p>Abstract</p> <p>Background</p> <p>Amifostine is an efficient cytoprotector against toxicity caused by some chemotherapeutic drugs. Doxorubicin, a potent anticancer anthracycline, is known to produce spermatogenic damage even in low doses. Although some studies have s...

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Bibliographic Details
Main Authors: Miraglia Sandra M, Sasso-Cerri Estela, Vendramini Vanessa
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/8/1/3