Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells

Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells

The implementation of rotating-wall vessels (RWVs) for studying the effect of lack of gravity has attracted attention, especially in the fields of stem cells, tissue regeneration, and cancer research. Immune cells incubated in RWVs exhibit several features of immunosuppression including impaired leu...

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Bibliographic Details
Main Authors: Maria Moreno-Villanueva, Alan H. Feiveson, Stephanie Krieger, AnneMarie Kay Brinda, Gudrun von Scheven, Alexander Bürkle, Brian Crucian, Honglu Wu
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
radiation
simulated microgravity
DNA damage response
adrenergic receptor
cytokines
Online Access:https://www.mdpi.com/1422-0067/19/11/3689

Internet

https://www.mdpi.com/1422-0067/19/11/3689

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