Interaction of Heavy Drinking Patterns and Depression Severity Predicts Efficacy of Quetiapine Fumarate XR in Lowering Alcohol Intake in Alcohol Use Disorder Patients

Background: Shared etiological pathways of dopamine and serotonin neurotransmission play a central role in heavy alcohol intake and exacerbation in the symptoms of depression. We investigated the treatment efficacy of Quetiapine fumarate extended release (XR) in lowering alcohol intake in alcohol us...

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Bibliographic Details
Main Authors: Vatsalya Vatsalya, Maiying Kong, Luis M Marsano, Zimple Kurlawala, Kan V Chandras, Melanie L Schwandt, Vijay A Ramchandani, Craig J McClain
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:Substance Abuse: Research and Treatment
Online Access:https://doi.org/10.1177/1178221820955185