Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Telomerase activation, a critical step in cell immortalization and oncogenesis, is partly regulated by alternative splicing. In this study, we aimed to use the Marek's disease virus (MDV) T-cell lymphoma model to evaluate TERT r...

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Bibliographic Details
Main Authors: Le Vern Yves, Dambrine Ginette, Remy Sylvie, Amor Souheila, Rasschaert Denis, Laurent Sylvie
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/571