Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

<p>Abstract</p> <p>Background</p> <p>Crosstalk between malignant hepatocytes and the surrounding peritumoral stroma is a key modulator of hepatocarcinogenesis and therapeutic resistance. To examine the chemotherapy resistance of these two cellular compartments <it>...

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Bibliographic Details
Main Authors: Rangwala Fatima, Williams Kevin P, Smith Ginger R, Thomas Zainab, Allensworth Jennifer L, Lyerly H, Diehl Anna, Morse Michael A, Devi Gayathri R
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Cancer
Subjects:
Hepatocellular carcinoma
Arsenic trioxide
Sorafenib
5-fluorouracil
Apoptosis
High throughput assay
Stroma
Online Access:http://www.biomedcentral.com/1471-2407/12/402

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http://www.biomedcentral.com/1471-2407/12/402

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