Cyclic tensile strain controls cell shape and directs actin stress fiber formation and focal adhesion alignment in spreading cells.

The actin cytoskeleton plays a crucial role for the spreading of cells, but is also a key element for the structural integrity and internal tension in cells. In fact, adhesive cells and their actin stress fiber-adhesion system show a remarkable reorganization and adaptation when subjected to externa...

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Bibliographic Details
Main Authors: Alexandra M Greiner, Hao Chen, Joachim P Spatz, Ralf Kemkemer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3810461?pdf=render