Synthesis of Hydroxymethylenebisphosphonic Acid Derivatives in Different Solvents
The syntheses of hydroxymethylenebisphosphonic acid derivatives (dronic acid derivatives) starting from the corresponding substituted acetic acids and P-reagents, mainly phosphorus trichloride and phosphorous acid are surveyed according to the solvents applied. The nature of the solvent is a critica...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-08-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/21/8/1046 |