Trans-Allelic Model for Prediction of Peptide:MHC-II Interactions

Major histocompatibility complex class two (MHC-II) molecules are trans-membrane proteins and key components of the cellular immune system. Upon recognition of foreign peptides expressed on the MHC-II binding groove, CD4+ T cells mount an immune response against invading pathogens. Therefore, mechan...

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Bibliographic Details
Main Authors: Abdoelnaser M. Degoot, Faraimunashe Chirove, Wilfred Ndifon
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01410/full