The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging

Sirtuin1 (SIRT1), which belongs to a highly conserved family of protein deacetylase, is one of the best-studied sirtuins. SIRT1 is involved in a variety of biological processes, including energy metabolism, cell proliferation and survival, chromatin dynamics, and DNA repair. In the vasculature, SIRT...

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Bibliographic Details
Main Authors: Andy W. C. Man, Huige Li, Ning Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01173/full