MNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1

The mechanistic target of rapamycin (mTOR) integrates numerous stimuli and coordinates the adaptive response of many cellular processes. To accomplish this, mTOR associates with distinct co-factors that determine its signaling output. While many of these co-factors are known, in many cases their fun...

Full description

Bibliographic Details
Main Authors: Michael C. Brown, Matthias Gromeier
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
MNK
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300608