Paclitaxel and naringenin-loaded solid lipid nanoparticles surface modified with cyclic peptides with improved tumor targeting ability in glioblastoma multiforme

Paclitaxel and naringenin-loaded solid lipid nanoparticles surface modified with cyclic peptides with improved tumor targeting ability in glioblastoma multiforme

The present work describes the systematic development of paclitaxel and naringenin-loaded solid lipid nanoparticles (SLNs) for the treatment of glioblastoma multiforme (GBM). So far only temozolomide therapy is available for the GBM treatment, which fails by large amount due to poor brain permeabili...

Full description

Bibliographic Details
Main Authors: Liying Wang, Xiangbo Wang, Lina Shen, Majed Alrobaian, Sunil K. Panda, Hussain A. Almasmoum, Mazen M. Ghaith, Riyad A. Almaimani, Ibrahim Abdel Aziz Ibrahim, Tanuja Singh, Abdullah A. Baothman, Hani Choudhry, Sarwar Beg
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Chemotherapeutics
Solid lipid nanoparticles
Experimental designs
Cyclic peptides
Glioblastoma
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221002468

Internet

http://www.sciencedirect.com/science/article/pii/S0753332221002468

Similar Items