Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota

Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota

Abstract Background Dysbiosis of the gut microbiota has been implicated in the pathogenesis of many autoimmune conditions including type 1 diabetes (T1D). It is unknown whether changes in the gut microbiota observed in T1D are due to environmental drivers, genetic risk factors, or both. Here, we hav...

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Bibliographic Details
Main Authors: Jane A. Mullaney, Juliette E. Stephens, Mary-Ellen Costello, Cai Fong, Brooke E. Geeling, Patrick G. Gavin, Casey M. Wright, Timothy D. Spector, Matthew A. Brown, Emma E. Hamilton-Williams
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Microbiome
Subjects:
Gut microbiota
Type 1 diabetes
Genetic susceptibility
Interleukin-2 pathway
Autoimmunity
Online Access:http://link.springer.com/article/10.1186/s40168-018-0417-4

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http://link.springer.com/article/10.1186/s40168-018-0417-4

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