Short Duplex Module Coupled to G-Quadruplexes Increases Fluorescence of Synthetic GFP Chromophore Analogues

Short Duplex Module Coupled to G-Quadruplexes Increases Fluorescence of Synthetic GFP Chromophore Analogues

Aptasensors became popular instruments in bioanalytical chemistry and molecular biology. To increase specificity, perspective signaling elements in aptasensors can be separated into a G-quadruplex (G4) part and a free fluorescent dye that lights up upon binding to the G4 part. However, current syste...

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Bibliographic Details
Main Authors: Snizhana O. Zaitseva, Nadezhda S. Baleeva, Timofei S. Zatsepin, Ivan N. Myasnyanko, Anton V. Turaev, Galina E. Pozmogova, Alexei A. Khrulev, Anna M. Varizhuk, Mikhail S. Baranov, Andrey V. Aralov
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Sensors
Subjects:
green fluorescent protein (gfp) chromophore
fluorogenic dye
g-quadruplex
quadruplex-duplex junction
aptamer
biosensors
Online Access:https://www.mdpi.com/1424-8220/20/3/915

Internet

https://www.mdpi.com/1424-8220/20/3/915

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