Phagocytosis of Advanced Glycation End Products (AGEs) in Macrophages Induces Cell Apoptosis

Advanced glycation end products (AGEs) are the products of a series of nonenzymatic modifications of proteins by reducing sugars. AGEs play a pivotal role in development of diabetic complications and atherosclerosis. Accumulation of AGEs in a vessel wall may contribute to the development of vascular...

Full description

Bibliographic Details
Main Authors: Yuan Gao, Hidenori Wake, Yuta Morioka, Keyue Liu, Kiyoshi Teshigawara, Megumi Shibuya, Jingxiu Zhou, Shuji Mori, Hideo Takahashi, Masahiro Nishibori
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/8419035