PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer
Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. P21-activated kinase 4 (PAK4) and miR-9-5p have emerged as attractive therapeutic targets in several tumor types, but in CRC, the regulation of their biological function and their target association rem...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s11658-019-0182-9 |