PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer

Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. P21-activated kinase 4 (PAK4) and miR-9-5p have emerged as attractive therapeutic targets in several tumor types, but in CRC, the regulation of their biological function and their target association rem...

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Bibliographic Details
Main Authors: Meihua Wang, Qianqian Gao, Yufang Chen, Ziyan Li, Lingping Yue, Yun Cao
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11658-019-0182-9